Arthus Phenomenon
What is an Example of the Arthus Reaction?
An example of the Arthus reaction is localized inflammation following a vaccine injection or insect bite.
What is the Difference Between Serum Sickness and Arthus Reaction?
Serum sickness is systemic, triggered by drugs, while the Arthus reaction is local and results from repeated antigen exposure.
What is Arthus Reaction Characterized by?
Arthus reaction is characterized by localized tissue injury due to immune complex deposition, leading to symptoms like erythema, edema, and tissue necrosis.
What is Arthus Phenomenon?
Arthus Phenomenon is a rare immunological condition that causes localized tissue injury as a result of immune complex deposition. It develops after several exposures to an antigen, resulting in an excessive immunological response.
What are Common Causes of Arthus Phenomenon?
Vaccinations (e.g., tetanus, diphtheria), occupational antigen exposure, latex allergy, sensitization to animal proteins, and specific drugs (e.g., antibiotics, vaccinations, biologics) are all common triggers.
What are the Symptoms of the Arthus Phenomenon?
The typical symptoms are erythema (skin redness), edema (swelling), localized discomfort, and, in severe cases, tissue necrosis and ulceration at the site of antigen exposure.
How is the Arthus Phenomenon diagnosed?
Clinical evaluation, patient history, and laboratory testing such as serum complement levels, immunoglobulin assays, and skin biopsies are used to confirm immune complex deposition and inflammation.
Arthus Phenomenon
Arthus phenomenon, named after the French immunologist Nicolas Maurice Arthus, is an uncommon immune response that causes localised damage to the tissue. Arthus phenomenon results from the deposition of the immune complex. This condition happens when an antigen is repeatedly administered resulting in an exaggerated immunological response.
In this article, we will learn about the Arthus phenomenon, its mechanisms, examples, and management, which is critical for physicians and researchers in addressing the condition.
Table of Content
- What is Arthus Phenomenon?
- Arthus Reaction Mechanism
- Arthus Reaction Symptoms
- Examples of Arthus Reaction
- Diagnosis of Arthus Phenomenon
- Treatment of Arthus Phenomenon
- Research and Future Directions
- Arthus Reaction Vs Serum Sickness
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