Diagnosis of Arthus Phenomenon
Some of the techniques used to detect Arthus phenomenon are:
Technique for Diagnosis |
Description |
---|---|
Patient History |
Obtaining full details on recent antigen exposures. |
Clinical Evaluation |
Evaluation of symptoms such as inflammation, redness, edema, and localized pain aid diagnosis. |
Patch Testing/ allergy testing |
Testing for specific antigens or allergens suspected to trigger Arthus Phenomenon |
Skin Biopsy |
Damaged skin tissue can be surgically removed and examined to observe any deposition of the immune complex |
Serum Complement Levels |
Measurement of complement proteins in the circulation. |
Immunoglobulin Assays |
Assays to evaluate immunoglobulin levels in serum to determine immune-mediated responses example ELISA. |
Histopathological Examination |
Tissue samples are examined microscopically to visualize immunological complexes and inflammation. |
Arthus Phenomenon
Arthus phenomenon, named after the French immunologist Nicolas Maurice Arthus, is an uncommon immune response that causes localised damage to the tissue. Arthus phenomenon results from the deposition of the immune complex. This condition happens when an antigen is repeatedly administered resulting in an exaggerated immunological response.
In this article, we will learn about the Arthus phenomenon, its mechanisms, examples, and management, which is critical for physicians and researchers in addressing the condition.
Table of Content
- What is Arthus Phenomenon?
- Arthus Reaction Mechanism
- Arthus Reaction Symptoms
- Examples of Arthus Reaction
- Diagnosis of Arthus Phenomenon
- Treatment of Arthus Phenomenon
- Research and Future Directions
- Arthus Reaction Vs Serum Sickness
Contact Us