Arthus Reaction Symptoms
The symptoms of Arthus Phenomenon can range from moderate to severe depending on the severity of the immune response along with the location of immune complex deposition. Some of the symptoms are mentioned below:
- Erythema: Redness of the skin at the point of exposure
- Edema: Swelling and fluid collection in the affected area
- Pain: Localized pain or discomfort at the location of antigen exposure
- Tissue Necrosis: In severe cases, tissue death and necrosis can occur
- Ulceration: The formation of ulcers near the site of inflammation
These signs often arise within 1-2 hours of antigen exposure and can last many days.
Arthus Phenomenon
Arthus phenomenon, named after the French immunologist Nicolas Maurice Arthus, is an uncommon immune response that causes localised damage to the tissue. Arthus phenomenon results from the deposition of the immune complex. This condition happens when an antigen is repeatedly administered resulting in an exaggerated immunological response.
In this article, we will learn about the Arthus phenomenon, its mechanisms, examples, and management, which is critical for physicians and researchers in addressing the condition.
Table of Content
- What is Arthus Phenomenon?
- Arthus Reaction Mechanism
- Arthus Reaction Symptoms
- Examples of Arthus Reaction
- Diagnosis of Arthus Phenomenon
- Treatment of Arthus Phenomenon
- Research and Future Directions
- Arthus Reaction Vs Serum Sickness
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