What is Inotropic?
The Inotropic Drug affects cardiac contractions. In the medical world, they are known as inotropes. They help in modifying the force of heart contractions. Positive inotropes and negative inotropes are the two types of inotropic drugs. Positive inotropes boost the strength of the heartbeat, whereas negative inotropes weaken it. Because they have opposing effects, both subtypes are widely used in the treatment of many cardiovascular conditions.
Examples of Inotropic:
- Digoxin is an inotropic agent that increases the strength of the heart’s contraction by modulating the calcium handling in cardiac muscle cells. It is commonly used in the management of heart failure.
- Dobutamine is also an inotropic agent that stimulates the beta-1 adrenergic receptors, leading to an increase in the force of contraction of the heart. It is used in the management of acute heart failure and cardiogenic shock.
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