What is a Chromosome?

A chromosome is a thread-like structure formed by the DNA molecule that undergoes a packaging process within the nucleus of every cell. In the chromosome, the DNA is tightly coiled many times around proteins called histones that support its structure. The chromosomes are visible in the cell’s nucleus only when it divides.

Each chromosome has a centromere, which divides the chromosome into two sections or arms. The short arm of the chromosome is called the p arm. The long arm of the chromosome is called the q arm. The location of the centromere on each chromosome gives the chromosome its characteristic shape. According to the position of the centromere, chromosomes are of four types namely Metacentric, Submetacentric, Acrocentric, and Telocentric.

Homologous Chromosome – Structure and Functions

Homologous chromosomes refer to paired chromosomes that essentially have the same gene sequence, gene position (loci), centromere location, and chromosomal length. Though they may have the same genetic sequence and loci they may differ in alleles. The pair is comprised of a paternal chromosome and a maternal chromosome.

Just like homologous chromosomes, there are heterologous chromosomes as well. So let us understand what a chromosome is and then further about homologous chromosomes, and how is it different from heterologous chromosomes. In this article, we will read about homologous chromosomes, their structure, functions, and much more.

Table of Content

  • Definition of Homologous Chromosomes
  • What is a Chromosome?
  • What are Homologous Chromosomes?
  • Example of Homologous Chromosomes
  • Structure of Homologous Chromosomes
  • Difference Between Homologous Chromosome and Heterologous (Non-Homologous) Chromosome
  • Sister Chromatids vs Homologous Chromosomes
  • Functions of Homologous Chromosome

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Definition of Homologous Chromosomes

Homologous chromosomes are a pair of chromosomes which have the same loci, gene sequence, chromosomal length and centromere location. They have the same genes but slightly different DNA....

What is a Chromosome?

A chromosome is a thread-like structure formed by the DNA molecule that undergoes a packaging process within the nucleus of every cell. In the chromosome, the DNA is tightly coiled many times around proteins called histones that support its structure. The chromosomes are visible in the cell’s nucleus only when it divides....

What are Homologous Chromosomes?

Homologous chromosomes are paired chromosomes that essentially have the same gene sequence, gene position technically called loci, centromere location, and chromosomal length. The pair consists of a paternal chromosome and a maternal chromosome. It is important to remember that the pairing of homologous chromosomes occurs only during meiosis and not during mitosis. The pairing is important for the accurate separation of chromosomes during meiosis....

Example of Homologous Chromosomes

Humans have 23 pairs of homologous chromosomes. One chromosome of each pair comes from the mother, while the other comes from the father. These chromosomes are carried in the haploid gametic cells called sperms and eggs. During fertilization, sperm and eggs fuse leading to the formation of a diploid organism. This zygote divides many times to create all of the cells of the human body. Each cell in the human body, thus, contains 23 pairs of homologous chromosomes, or 46 chromosomes in total....

Structure of Homologous Chromosomes

The basic parts of a homologous chromosome are centromere also called kinetochore, short arm p, and long arm q. The length of the arm and the position of the centromere have an important role in determining the homogeneity of the chromosomes. As stated above based on the position of the centromere there are four types of chromosomes, thus, the two chromosomes with similar structures come together to form homologous chromosomes. It should be noted that homologous chromosomes are not identical chromosomes like the sister chromatids....

Difference Between Homologous Chromosome and Heterologous (Non-Homologous) Chromosome

The difference between homologous and heterologous chromosomes are stated below:...

Sister Chromatids vs Homologous Chromosomes

There lies a difference between homologous chromosomes and sister chromatids. As discussed above homologous chromosomes are pair of chromosomes that have the same structure and genes but may have different alleles of those genes. Whereas, sister chromatids are identical copies of a single chromosome. They are formed during the DNA replication process that occurs before cell division. Each chromosome consists of two identical sister chromatids which are connected by a protein complex called the centromere....

Functions of Homologous Chromosome

The functions of Homologous Chromosome are as follows:...

Conclusion – Homologous Chromosome

Homologous chromosomes are chromosomes having the same genetic makeup. The homologous chromosomes are vital for diagnosing genetic disorders. Thus it can be concluded that homologous chromosomes are chromosomes that have the same genetic organization. They contribute to genetic diversity, recombination, exchange of genetic material, and much more. This leads to the enhancement of the gene pool and increases the adaptation ability of the organism towards changing environmental conditions for the survival of the organism....

FAQs on Homologous Chromosome

What are Homologous Chromosome ?...

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