Mendelian Disorders
Mendelian disorders are also known as Mendelian diseases or monogenic disorders. They are genetic diseases caused by mutations in a single gene and follow Mendel’s laws of inheritance i.e., they are typically inherited in a predictable pattern based on the principles of dominance, recessive, or X-linked inheritance. They are typically categorised into five major groups based on their pattern of inheritance. These are Autosomal dominant disorders, Autosomal recessive disorders, Sex-linked dominant disorders, sex-linked recessive disorders and mitochondrial disorders.Some common examples of Mendelian disorders are haemophilia, phenylketonuria, etc.
Also Read: Difference Between Chromosome and Gene
Types of Mendelian Disorders in Humans and Examples
Mendelian disorders in humans are genetic conditions that follow Mendel’s laws of inheritance, resulting from mutations in a single gene. Common examples of Mendelian disorders are hemophilia, cystic fibrosis, thalassemia, etc. These disorders adhere to predictable patterns of transmission, either through autosomal dominant, autosomal recessive, or X-linked inheritance.
Understanding these Mendelian disorders in humans helps us understand the relationship between genes and phenotypes and guides medical research to promote health and prevent disease. In this article, we will study Mendelian Disorder, the Principles of Mendelian Disorders, and the examples of Mendelian Disorder in detail.
Table of Content
- Mendelian Disorders
- Principles of Mendelian Disorders
- Types of Mendelian Disorders
- Examples of Mendelian Disorders in Humans
- Conclusion
- FAQs on Mendelian Disorders in Humans
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