General Features of Inclusion Bodies in Cell

What are Inclusion Bodies?

Inclusion bodies are found in cells. They are formed when the pH of soluble fusion protein within cells decreases. Typically, they are formed in the virus-infected cells during infection. Inclusion bodies in cell are non-living and are composed of cellular metabolism by-products. Glycogen granules, phosphate granules, gas vacuoles, and cyanophycean granules are a few classic examples of inclusion bodies. Based on the cell type, inclusion body composition and function varies....

General Features of Inclusion Bodies in Cell

Common features of inclusion bodies are as follows:...

Functions of Inclusion Bodies

It performs various functions depending on the type of organism and the specific inclusion body. Some common functions of inclusion body are given below:...

Classification of Inclusion Bodies

Inclusion bodies can be present in prokaryotic and eukaryotic cells either in the cytoplasm or within the nucleus. Some inclusion bodies are formed during infection when the foreign microorganism infects the human cells. However, some inclusion bodies are formed during cell metabolism. Inclusion bodies in cell act as storehouses of certain metabolites or metabolic byproducts. Different types of Inclusion bodies are discussed further:...

Inclusion Bodies Examples

Some examples of each type of inclusion body is given as follows:...

Diseases Associated With Inclusion Bodies

Although storing cellular metabolites can serve a positive function for human cells, a deviation in natural balance can lead to certain disorders or health problems. Inclusion bodies cannot be confused with amyloid bodies which are also protein aggregates. The main difference is that amyloid accumulation involves polymerisation and can be intra or extracellular. However, inclusion bodies do not mandatorily need polymerisation and are specifically intracellular. Extracellular accumulations are not considered inclusion bodies....

Conclusion: Inclusion Bodies – Features, Classification and Examples

An inclusion body is a distinct structure found within cells that is often comprised of aggregated proteins, viral particles, or other substances. These bodies can vary widely in composition, size, and function, and they are observed across different organisms, including bacteria, viruses, fungi, protozoa, and human cells. Inclusion bodies are commonly associated with pathological conditions, but they can also serve physiological roles within cells like storage. They are an interesting topic of research and are still being studied to understand their mechanisms in depth....

FAQs on Inclusion Bodies

What are Inclusion Bodies Class 11?...