Functions of Albumin

Albumin is a major plasma protein which performs several crucial functions in the body:

Oncotic Pressure Regulation

  • Albumin plays a crucial role in maintaining the oncotic pressure in the blood vessels.
  • This pressure gradient helps to keep water within the blood vessels, preventing excessive fluid leakage into the tissues.

Transport function

  • It acts as a carrier protein, transporting various substances in the bloodstream.
  • For example, it binds to fatty acids, facilitating their transport, and it also binds to bilirubin, aiding in its transport to the liver for excretion.

pH Regulation

Albumin helps to buffer changes in blood pH by binding to hydrogen ions (H⁺) and other ions, contributing to the maintenance of normal blood pH levels.

Antioxidant properties

  • Albumin has the capacity to bind and transport certain metals (e.g., copper, nickel), preventing them from participating in oxidative reactions that could damage tissues.
  • It also binds and inactivates some free radicals, exhibiting antioxidant properties.

Anticoagulant properties

Albumin binds to certain coagulation factors, modulating their activity and contributing to the regulation of blood coagulation.

Nutritional reserve

Albumin serves as a reserve of amino acids that can be used by the body in times of nutritional deficiency or increased metabolic demand.

Albumin in Urine

Albumin is a major blood protein that is produced in the liver. Albumin is the most abundant blood plasma protein, accounting for 55% of the total protein in plasma. Understanding albumin in urine causes and symptoms involves recognizing that albuminuria, or the presence of albumin in urine, can indicate kidney damage or dysfunction, often linked to conditions like diabetes, hypertension, or kidney disease.

Table of Content

  • What is Albumin?
  • Structure of Albumin
  • Albumin in Urine – Albuminuria
  • Albumin in Urine Symptoms
  • Albumin in Urine Causes
  • Treatment for Albuminuria
  • Albumin in Urine Normal Range
  • Albumin in Urine Test
  • How to Reduce Albumin in Urine
  • Functions of Albumin

Similar Reads

What is Albumin?

Albumin is the most prominent circulating protein in plasma. It is a globular protein which constitutes half of the total protein content (3.5 to 5 g/dL) of plasma in humans. Albumin is produced by liver hepatocytes and promptly discharged into the circulation at a rate of 10 to 15 grams per day. The liver stores very little albumin, and the vast majority of it is quickly discharged into the circulation....

Structure of Albumin

Albumin has a globular structure, with a single polypeptide chain folded that consists of three homologous domains that combine to produce a heart-shaped protein. Each domain is composed of two subdomains that share structural features. The primary ligand binding sites on human serum albumin are situated in hydrophobic cavities in subdomains IIA and IIIA, which have comparable chemistry....

Albumin in Urine – Albuminuria

Albumin in the urine, known as albuminuria (sometimes referred to as proteinuria), is an indicator of kidney dysfunction or damage. Albumin is a protein that is normally found in the blood, and healthy kidneys filter out waste products from the blood while preventing the loss of albumin in the urine....

Albumin in Urine Symptoms

Most patients with albuminuria (proteinuria) may have no symptoms. If symptoms are present, you may observe any of the following:...

Albumin in Urine Causes

Some of the most prevalent causes of transitory (short-term) albuminuria are:...

Treatment for Albuminuria

Treatment for albuminuria typically involves managing the underlying cause, such as controlling blood sugar levels in diabetes or managing blood pressure. Lifestyle changes, such as adopting a healthy diet, exercising regularly, and avoiding smoking, can also help protect kidney function....

Albumin in Urine Normal Range

The normal range for albumin in urine is less than 30 milligrams per gram (mg/g) of creatinine. This is often expressed as less than 30 milligrams per gram of creatinine (mg/g Cr) in a spot urine sample....

Albumin in Urine Test

The albumin levels in urine are checked with a simple urine sample. No special collection or preparation is necessary before this test, and only about 2 tablespoons of urine are needed....

How to Reduce Albumin in Urine

Reducing albumin in the urine involves addressing the underlying conditions or factors contributing to its elevation. Some of the ways of reducing urine in albumin in urine are:...

Functions of Albumin

Albumin is a major plasma protein which performs several crucial functions in the body:...

Conclusion – Albumin in Urine

Albumin in urine serves as a vital marker for kidney health, with elevated levels often indicating underlying kidney damage or dysfunction. Understanding the significance of albuminuria involves recognizing its association with conditions such as diabetes, hypertension, or kidney disease. Diagnosis typically relies on urine tests such as the urine albumin-creatinine ratio (uACR), while further assessments like kidney biopsy or imaging studies may be necessary for a comprehensive evaluation. Regular monitoring and collaboration with healthcare professionals are essential for optimal management and prevention of complications related to elevated albumin levels in urine....

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