Pleiotropy
Q1: What type of inheritance is pleiotropy?
Answer:
Pleiotropy is a form of complicated genetic inheritance where one gene influences a variety of attributes. The genotype, or genetic makeup of an organism, governs the phenotype, or expressed trait.
Q2: What is the importance of pleiotropy?
Answer:
Pleiotropy is crucial to improving our knowledge of human biology and disease. Pleiotropy is prevalent in the human genome, according to the findings of genome-wide association studies (GWASs).
Q3: How can genes show pleiotropy?
Answer:
Pleiotropy refers to when a genetic variation affects two or more attributes through separate biological pathways, such as when it affects different tissues or when it is causally linked to variation in another trait.
Q4: What is the common disease of pleiotropy?
Answer:
Marfan syndrome, which is brought on by a change in the FBN1 gene, serves as an illustration. Marfan syndrome patients frequently have long, thin fingers, toes, and limbs. But, they are also more likely to experience a wide range of symptoms, such as heart defects and issues with the eyes and spine.
Pleiotropy – An Overview and Related Disorders
‘PLEIOTROPY‘ term refers to the phenomenon in which a single locus affects two or more apparently unrelated phenotypic traits and is frequently identified as a single mutation affecting two or more wild-type traits. Pleiotropy comes from the Greek words pleio, which means “many,” and tropic, which means “affecting.” Pleiotropic genes are those that affect multiple, seemingly unrelated phenotypes. Pleiotropy should not be confused with polygenic traits, which occur when multiple genes interact to produce a single phenotype. Let’s have a glance at the topic of pleiotropy in detail.
Contact Us