Distribution in protein

  • Standard protein amino acids: The amino acids, which are recognized by ribozyme auto aminoacylation systems, are used to form proteins. Example: Methionine, Histidine, Lysine, Isoleucine, Leucine, Threonine, Tryptophan, Phenylalanine, and valine.
  • Non-standard protein amino acids: Amino acids don’t form proteins, but have a vital role in metabolic intermediates. Example: Hydroxylysine, Carboxyglutamate.
  • Non-standard nonprotein amino acids: These are the derivative of amino acids and have a role in metabolism. Example: Alpha amino butyrate, Ornithine, beta-alanine.

What are Amino Acids?

Amino Acids are essential for the human body. Amino acids are important in the formation of the structure of proteins. When a person eats foods that contain protein, the digestive system breaks down the protein into amino acids. The body then combines amino acids in various ways to perform physical functions. The body needs 20 amino acids to maintain good health and normal functioning. A healthy body can make only 11 amino acids on its own, but the other 9 amino acids cannot be synthesized by the body. The other 9 amino acids must be ingested from the other sources through food. A body that can make amino acids are called non-essential amino acids because it creates on its own. The amino acids which cannot make owned by the body are called essential amino acids because they are taken from other sources. Amino acids are an essential part of the functioning of various chemical and biological of our body. The different functions include transportation of molecules, building, and fixing of the tissues, development, and capability of enzymes, food digestion, and so on. These biomolecules are important elements for the development and advancement of individuals. There are around 300 amino acids that can be tracked down in nature. Be that as it may, just 20 amino acids are significant.

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Amino Acids

Amino acids are organic compounds containing amine (- NH2), carboxyl (-COOH), and side chain—R group. The major elements of amino acids are carbon, hydrogen, nitrogen, and oxygen. Each molecule contains a central carbon atom, α-carbon to which both an amino and a carboxyl group are attached. The other two bonds of the α-carbon atom are bonded by a hydrogen (H) atom and the R group. All amino acids have the alpha carbon bonded to a hydrogen atom, carboxyl group, and amino group. The R group (side chain) varies among amino acids.  The structure of amino acids is represented below....

Classification and Types

The different types of amino acids are classified based on...

Based on nutritional requirements

Essential Amino Acids...

Based on R-Group

Simple amino acids: These amino acids don’t have a functional group in their side chain. Example: valine, isoleucine. Hydroxy amino acids: Presence of hydroxyl group in their side chain. Example: serine, threonine. Sulfur-containing amino acids: They contain sulfur in their side chain. Example: cysteine, methionine. Aromatic amino acids: These amino acids contain a benzene ring in their side chain. Example: phenylalanine, tyrosine. Heterocyclic amino acids: Amino acids have a side chain ring that contains at least one atom other than carbon. Example: Tryptophan, histidine, proline. Amine group-containing amino acids: The derivatives of amino acids in which one of the carboxyl groups have been transformed into an amide group. Example: Asparagine, glutamine. Branched-chain amino acids (BCAAs): BCAAs are the amino acids that contain aliphatic side-chains with a branch. Example: isoleucine, valine. Acidic amino acids: Amino acids have a carboxyl group in their side chain. Example: Aspartic and Glutamic acid. Basic amino acids: Amino acids have an amino group in their side chain. Example: Lysine, Arginine. Amino acid: Amino acids consists of a secondary amine group. Example: Proline....

Polarity and R Group

Amino acids with non-polar R group: These amino acids are hydrocarbons in nature  Aliphatic R groups – Alanine, Valine, Leucine, Isoleucine, Proline. Aromatic groups—Phenylalanine, Tryptophan, Methionine (sulfur). Amino acids with polar but uncharged R Group: Amino acids are polar and have a neutral pH value. Example: Serine, Threonine, Tyrosine. Negatively charged amino acids: The side chain of amino acids has an extra carboxyl group with a dissociable proton. Example: Aspartic acid and Glutamic acid Positively charged amino acid: The side chain of an amino acid has an extra amino group, which gives basic nature to protein. Example: Lysine, Arginine, Histidine....

Distribution in protein

Standard protein amino acids: The amino acids, which are recognized by ribozyme auto aminoacylation systems, are used to form proteins. Example: Methionine, Histidine, Lysine, Isoleucine, Leucine, Threonine, Tryptophan, Phenylalanine, and valine. Non-standard protein amino acids: Amino acids don’t form proteins, but have a vital role in metabolic intermediates. Example: Hydroxylysine, Carboxyglutamate. Non-standard nonprotein amino acids: These are the derivative of amino acids and have a role in metabolism. Example: Alpha amino butyrate, Ornithine, beta-alanine....

Physical Properties

They are colorless. Amino acids are crystalline in nature. They are tasteless and sweet in nature. Amino acids have a melting point of above 200˚C. They are soluble in polar solvents like water, acetone, methanol, etc. They are insoluble in non-polar solvents like alkanes, acetic acids, chloroforms, etc. Amino acids have absorbance at 280 nm. The Molecular weight of amino acids is from 100 to 50,000Dt. They exhibit colloidal nature and denaturing properties....

Chemical Properties

Decarboxylation...

Deficiency of Amino acids

Amino acids are the structure blocks of proteins, and proteins assume a key part in practically all life processes. In this way, it is important to remember every one of the nine essential amino acids for our day-to-day diet to keep a solid and legitimate capability of our body. The lack of amino acids might incorporate different neurotic problems, including Enema, Anemia, Insomnia, Diarrhea, Depression, Hypoglycemia, Loss of Appetite, Fat stored in the liver, Skin and hair-related issues, Headache, shortcoming, peevishness, and weariness....

Food Sources

Foods that incorporate high amounts of amino acids include...

Frequently Asked Questions

Question 1: What is the importance of amino acids?...

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