Core Difference between Centromere and Kinetochore
The following are some major differences between Centromere and Kinetochore:
- A kinetochore is a protein complex that binds to the centromere, which is the primary region of condensed chromosomes.
- Under a light microscope, the centromere is clearly visible, whereas an electron microscope makes the kinetochore visible.
- Kinetochore is one kinetochore complex, whereas centromere can be either monocentric or holocentric.
- Centromere is made up of centric heterochromatin, whereas the kinetochore is constructed from certain histone subtypes.
Difference Between Centromere and Kinetochore
Centromere and Kinetochore are the two primary structures located in the approximate middle of chromosomes. At the time of cell division, they are extremely important for sister chromatid segregation. The primary difference between Centromere and Kinetochore is that the centromere is the region of the chromosome that holds two sister chromatids, whereas the kinetochore is the disc-shaped protein complex of the chromosome.
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