What is Cushing Syndrome?
The Cushing syndrome is a collection of clinical symptoms that frequently co-occur because of excessive glucocorticoid receptor stimulation. When the body consistently produces too much cortisol, Cushing syndrome develops. Taking oral corticosteroid medicine may cause this. Alternatively, the body could make too much cortisol.
Several of the defining characteristics of Cushing syndrome, such as a fatty hump between the shoulders, a round face, and pink or purple stretch marks on the skin, can be brought on by an excess of cortisol. In some cases, type 2 diabetes, high blood pressure, and bone loss are also side effects of Cushing syndrome.
Difference Between Addison’s Disease and Cushing’s Syndrome
The main distinction between Addison syndrome and Cushing’s disease is that Cushing’s syndrome exhibits an excess of cortisol while Addison’s disease exhibits a hormonal deficiency of cortisol and aldosterone. To correctly diagnose and treat Addison’s disease and Cushing’s syndrome, it’s critical to understand their differences. The hypofunction of the adrenal gland, which may be brought on by primary adrenocortical insufficiency or a lack of pituitary adrenocorticotropic hormone (ACTH) release, is the underlying cause of Addison’s disease. On the other hand, overproduction of the hormone cortisol in the body results in Cushing’s syndrome. Let’s have a glance at both topics in detail.
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