Indirect Bilirubin
Indirect bilirubin, additionally referred to as unconjugated bilirubin, is produced directly by the breakdown of hemoglobin, a component of red blood cells. This kind of bilirubin binds to a protein called albumin, which helps carry it from the bloodstream to the liver. However, indirect bilirubin is extremely hazardous. So, in the liver, enzymes convert it into a less toxic version known as direct bilirubin.
Indirect bilirubin can dissolve in fat but not water. Several factors can cause bilirubin levels to increase, including Red blood cell breakdown also known as hemolytic anaemia, skin injuries may result in bleeding, lung haemorrhage, and genetic diseases.
Causes of Indirect Bilirubin Increase
Indirect bilirubin increases due to excessive Red Blood Cells breakdown, genetic conditions, liver cells not working right and neonatal jaundice. Few genetic disorders like Gilbert’s syndrome and Crigler-Najjar syndrome can also result in increased indirect bilirubin.
Difference between Direct and Indirect Bilirubin
The difference between direct and indirect bilirubin lies in the fact that direct bilirubin is the type of bilirubin the human body can easily remove. It is similar to waste that the body can easily handle and eliminate, but indirect bilirubin is bilirubin combined with a protein in the bloodstream. It makes it tough for the body to eliminate. It is comparable to bilirubin, which requires a specific host before getting out of the body. In this article, we will look into the differences between direct and indirect bilirubin.
Table of Content
- What is Bilirubin?
- Direct Bilirubin
- Indirect Bilirubin
- Levels of Bilirubin
- Abnormal Levels of Bilirubin
- Difference Between Direct and Indirect Bilirubin
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