Direct Bilirubin
Direct bilirubin, also referred to as conjugated bilirubin, is a modified version of a chemical created when red blood cells are broken down. The enzyme glucuronyltransferase attaches glucuronic acid to bilirubin, making it less toxic and easier for the body to eliminate. Direct bilirubin dissolves in water.
The overall amount of bilirubin in our bodies comprises both direct and indirect forms. The bilirubin normal range in adults are:
Total Bilirubin Normal Range
The total bilirubin normal range is 0.1-1.2 mg/dL. But slightly higher levels are observed in newborns.
Direct Bilirubin Normal Range:
The direct bilirubin normal range falls between 0.0-0.3 mg/dL. A higher direct bilirubin level indicates an underlying issue with the liver, bile ducts. or gallbladder.
Causes of Direct Bilirubin Increase
Direct bilirubin increases due to liver diseases like hepatitis, cirrhosis, bile duct blockage, and excessive breakdown of Red Blood Cells etc. Some genetic diseases like Dubin-Johnson syndrome and Rotor syndrome can also cause increase in direct bilirubin.
Also Read: Disorders Of Digestive System
Difference between Direct and Indirect Bilirubin
The difference between direct and indirect bilirubin lies in the fact that direct bilirubin is the type of bilirubin the human body can easily remove. It is similar to waste that the body can easily handle and eliminate, but indirect bilirubin is bilirubin combined with a protein in the bloodstream. It makes it tough for the body to eliminate. It is comparable to bilirubin, which requires a specific host before getting out of the body. In this article, we will look into the differences between direct and indirect bilirubin.
Table of Content
- What is Bilirubin?
- Direct Bilirubin
- Indirect Bilirubin
- Levels of Bilirubin
- Abnormal Levels of Bilirubin
- Difference Between Direct and Indirect Bilirubin
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