Difference between Granulocyte and Agranulocyte

Granulocytes

Agranulocytes

Definition 

Contain granules in the cytoplasm. Does not contain granules in the cytoplasm.

Cells Produces

Basophils, Neutrophils, Eosinophils. Monocytes and Lymphocytes.

Immunity 

Granulocytes are involved in innate immunity. Agranulocytes involve in adaptive immunity.

Origin

Originates from Bone marrow. Originates from lymph nodes.

Nucleus

Granulocytes are known as polymorphonuclear leukocytes. Agranulocytes are known as mononuclear leukocytes.

Antibodies Response

Produces Histamine. Doesn’t Produces histamine

Most-Effective 

Can Kill parasites. Can’t kill Parasites.

Cells Produced

Produces from myeloid stem cell Produces from a lymphoid stem cell.

Type of Immunity 

Innate general Immunity. Specific and Humoral Immunity.

Concentration 

65% of total leukocytes. 35% of total leukocytes.

Enzymes Present 

Contain enzyme, Phagocytic particles & Inflammatory responses. Contain enzyme in lysozyme.

Summary

Granulocytes are the WBCs that help fight against infection they have their own specific enzymes. It increases the response to infection. Agranulocytes need recognition by leucocytes and they can kill pathogens as well as cells. They can be distinguished by the stain and presence of granules it can be observed under a light microscope.  Difference between each of every cell according to their specific function for phagocytic, allergic response, etc.

Difference Between Granulocytes And Agranulocytes

The first line of defense in the human body is WBCs which are also known as leukocytes are the cells of the immune system. It circulates throughout the blood and lymphatic system. Leukocyte plays important role in the immune system by identifying, destroying, and removing pathogens and damaged cells. These cells can leave blood cells and migrate through body fluids. Leukocytes originate in the bone marrow and circulate in lymph nodes.  Leukocytes can be characterized by the presence and absence of granules (Sacs containing digestive enzymes or other chemical substances) in the cytoplasm. If there is the presence of granules are granulocytes and if there absence of granules they are called agranulocytes.  Granulocytes include Eosinophile, Neutrophiles, and basophils. Agranulocytes are monocytes and lymphocytes.

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Difference between Granulocyte and Agranulocyte

Granulocytes Agranulocytes Definition  Contain granules in the cytoplasm. Does not contain granules in the cytoplasm. Cells Produces Basophils, Neutrophils, Eosinophils. Monocytes and Lymphocytes. Immunity  Granulocytes are involved in innate immunity. Agranulocytes involve in adaptive immunity. Origin Originates from Bone marrow. Originates from lymph nodes. Nucleus Granulocytes are known as polymorphonuclear leukocytes. Agranulocytes are known as mononuclear leukocytes. Antibodies Response Produces Histamine. Doesn’t Produces histamine Most-Effective  Can Kill parasites. Can’t kill Parasites. Cells Produced Produces from myeloid stem cell Produces from a lymphoid stem cell. Type of Immunity  Innate general Immunity. Specific and Humoral Immunity. Concentration  65% of total leukocytes. 35% of total leukocytes. Enzymes Present  Contain enzyme, Phagocytic particles & Inflammatory responses. Contain enzyme in lysozyme....

FAQs on Granulocyte and Agranulocyte

Question 1:  Which type of stain is used to detect Eosinophils?...

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