Difference Between Addison’s Disease and Cushing’s Syndrome?
Addison’s Disease |
Cushing’s Syndrome |
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Definition | Having insufficient cortisol (and aldosterone) results in Addison’s disease. | Having much cortisol results in Cushing’s syndrome (hypercortisolism). |
Signs and Symptoms |
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Predisposing factors |
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Diagnostics |
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Causes |
Auto immune due to the adrenal cortex becoming damaged due to the body attacking itself:
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Difference Between Addison’s Disease and Cushing’s Syndrome
The main distinction between Addison syndrome and Cushing’s disease is that Cushing’s syndrome exhibits an excess of cortisol while Addison’s disease exhibits a hormonal deficiency of cortisol and aldosterone. To correctly diagnose and treat Addison’s disease and Cushing’s syndrome, it’s critical to understand their differences. The hypofunction of the adrenal gland, which may be brought on by primary adrenocortical insufficiency or a lack of pituitary adrenocorticotropic hormone (ACTH) release, is the underlying cause of Addison’s disease. On the other hand, overproduction of the hormone cortisol in the body results in Cushing’s syndrome. Let’s have a glance at both topics in detail.
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