Causes of Amyloidosis
Causes of amyloidosis includes:
- Abnormal Protein Production: Primary (AL) amyloidosis occurs when abnormal plasma cells in the bone marrow produce excess immunoglobulin light chains, which form amyloid fibrils.
- Chronic Inflammatory or Infectious Conditions: Secondary (AA) amyloidosis develops in response to chronic inflammatory diseases, such as rheumatoid arthritis, inflammatory bowel disease, or chronic infections like tuberculosis.
- Aging and Degenerative Disorders: Senile systemic amyloidosis is associated with aging and the accumulation of wild-type transthyretin (TTR) amyloid deposits, primarily affecting the heart.
- Long-Term Dialysis Treatment: Dialysis-related amyloidosis occurs in individuals undergoing long-term hemodialysis or peritoneal dialysis for end-stage renal disease.
- Unknown Causes (Idiopathic): Idiopathic cases may involve a combination of genetic predisposition, environmental factors, or other underlying conditions that contribute to abnormal protein folding and amyloid formation.
Also Read: Disease causing Microorganisms in Humans
Amyloidosis
Amyloidosis is a rare disease characterized by the abnormal accumulation of amyloid proteins in organs and tissues. This buildup can disrupt normal function and lead to organ damage. Amyloidosis symptoms may include weight loss, swelling, and organ dysfunction.
Amyloidosis treatment helps to manage symptoms, slow the progression of the disease, and address underlying conditions that may contribute to amyloidosis. In this article, we will study the meaning of amyloidosis, its types, stages of development, causes, symptoms, and treatment in detail.
Table of Content
- Amyloidosis Meaning
- Types of Amyloidosis
- Stages of amyloidosis
- Causes of Amyloidosis
- Symptoms of Amyloidosis
- Diagnosis of Amyloidosis
- Treatment of Amyloidosis
- Conclusion: Amyloidosis
- FAQs on Amyloidosis
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